The Human Endocannabinoid System

We should thank the late President Reagan for his ‘War on Drugs” campaign.

You may not be aware of this interesting fact that has benefited all of us.

In the 1980’s, President Reagan poured tens of millions of dollars into a study to prove that marijuana damages the human brain, the Reagan administration ended up subsidizing a series of studies that culminated in the discovery of the endocannabinoid system. The endocannabinoid system (ECS) is a collection of cell receptors and the corresponding molecules (agonists) in the human body. This system helps to regulate appetite, fertility, immune function, memory, mood, motor control, pain, pleasure, reproduction, sleep and temperature regulations. When the ECS is in balance, one experiences homeostasis.

Endocannabinoids are molecules that act as chemical messengers that bind to cannabinoid cell receptors and tell the body to do certain things. The human naturally produces endocannabinoids with the help of consuming foods like fatty acids found in nuts and fish. The 60 cannabinoid also can bind to the cannabinoid receptors that cause different effects. The molecules found in cannabis/hemp plants aid in the human body’s endocannabinoid system, which is responsible for many vital functions.


LEFT SIDE OF YOUR BODY                                                                                  RIGHT SIDE OF YOUR BODY

Central Nervous System                                                                                                       Peripheral Nervous System

Brain/CNS/Spinal Cord                                                                                                         Eye

Cortical regions                                                                                                                    Stomach

Cerebellum                                                                                                                           Heart

Brainstem                                                                                                                             Pancreas

Basal ganglia                                                                                                                        Digestive tract

Olfactory bulb

Thalamus                                                                                                                             NON-CBD1 &  CBD2 ARE

Hypothalamus                                                                                                                     located in cells of:

Pituitary                                                                                                                               Blood vessels and arterial blood vessels

Thyroid                                                                                                                                CBD2 receptors located in cells of:

Upper airways                                                                                                                      Lymphatic and Immune Systems

Liver                                                                                                                                     Spleen, Thymus, Tonsils and Blood (lymphocytes)

Adrenals                                                                                                                              Non-Immune Cell CBD2 receptors found in

Ovaries                                                                                                                                Skin keratinocytes




CBD specifically interacts with the CBD1 & CBD2 receptors that send signals to wake up and strengthen the immune systems naturally.


Spinal Cord– controls Peripheral sensation including pain

Medulla– controls Nausea and Vomiting, chemoreceptor

Cerebellum– controls Movement

Cerebral Cortex– controls Higher cognitive function

Basal Ganglia- controls Movement

Hypothalamus- controls Appetite

Hippocampus– controls Learning, memory, stress

Thi is because our endocannabinoid system is intricately linked to our nervous system and immune system, as well as our brain and digestive system. Quality CBD is an effective form of natural treatment to many ailments and illnesses.